CBD & MOOD
When you think of CBD, one of the first things that comes to mind is likely to be its purported effects on mood. Millions of people all over the world use CBD products on a daily basis to help maintain an air of calm and happiness – something which can be a challenge in the face of modern day stressors, particularly after the year we’ve just had.
But does CBD really make a difference to our emotional balance? And if so, how?
As with every studied benefit of the cannabis sativa plant La Rue Verte CBD oil is derived from, it’s clear that the CBD molecule and 120+ other cannabinoids work in various unique ways with the human body. There’s not one action cannabis has which restores equilibrium in the mind and body, but many. In this blog we’re going to take a look at a few mood-balancing mechanisms that have been discovered in the incredible 41,000 studies now conducted on cannabis and the endocannabinoid system.
Did you know?
There have been more studies delving into the inner workings of cannabis and the endocannabinoid system than any pharmaceutical drug or physiological system.
The Bliss Molecule
We’ve said in before and we’ll say it again – one of the most amazing things about the cannabis plant is the way cannabinoids (like CBD) nudge the body into proper function. Through a completely unique interaction with the endocannabinoid system, CBD oil gives you the support you need to sort things out, naturally. This leads to our natural state of homeostasis, unlike many pharmaceuticals which often replace what’s missing or supress something that’s overactive eventually leading to further imbalances down the line.
When it comes to mood, this action which plays a huge part in reduce stress and enhancing joy. Upon taking a dose of CBD oil, the CBD molecule swiftly attaches to certain receptors through our in-built endocannabinoid system. But rather than fitting like a lock and key to trigger activity (like THC) it binds ‘imperfectly’, meaning it blocks the entry for its usual inhabitant – our own endocannabinoid anandamide (also known as the bliss molecule). Now, although this may sound unhelpful, in actual fact it’s this mechanism which then supports the release and longevity of anandamide in our bloodstream. This is further sustained by CBDs inhibition of the FAAH enzyme which would ordinarily (rapidly) break anandamide down.
So, what happens when we allow our bodies to enjoy an extra surge of anandamide? Stress is not only reduced, but our ability to manage stressful situations can change (read more about that is our blog covering Stress Management. Our mood is elevated, thanks to a rush of bliss that anandamide imparts. And perhaps most importantly, we are presented with a chance to replenish depleted levels of endocannabinoids, which cannabis expert Ethan Russo believes lies at the root cause of many, many mental and physical ailments.
CBD & Serotonin
Although CBD sits imperfectly in ECS receptors, it does fit like a lock and key in others, including serotonin receptors. This gives the go ahead to release feel-good chemical serotonin, which is responsible for regulating a variety of functions, including mood, sleep, digestion, sexual function and memory. Having healthy amounts of serotonin released in the body is vital for stable mood and an overall sense of wellbeing.
One little known fact about serotonin is that, although it’s considered to be a brain chemical, the intestines make about 95% of your body’s supply of it! Because of this a healthy diet, along with food supplements like CBD, can go a long way in ensuring appropriate serotonin levels.
Can CBD be used with SSRIs?
There is still a big question mark over interactions between CBD and pharmaceutical drugs, but as time goes by and more studies are performed we are starting to form some cogent answers. Most medical cannabis experts believe that CBD is safe, non-toxic and fine to use alongside most medications, although there is evidence to suggest that CBD in very high doses may slow down the metabolism and flushing of pharmaceutical drugs. This is caused by CBD inhibiting the activity of cytochrome P450, a family of liver enzymes.
However, there is a lot of ‘real world evidence’ to suggest that taking CBD with SSRIs presents no issue. They’re a very common combo, given CBD’s well-documented, positive impact on stress, depression and anxiety and plenty of doctors and researchers who know their stuff about cannabis happily prescribe the two together.
The choice is ultimately yours, but as ever with CBD the key is to start low and go slow – build up your dose gradually, keep a journal of your experience to note any changes to your mood and overall wellbeing, and find the amount that works best for you.
Want to know more about CBD dosage? You’ll find everything you need to know here.